Search on: NADP-DEPENDENT HYDROXYMETHYLGLUTARYL-COA-REDUCTASES 
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Descriptor English:   Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent 
Descriptor Spanish:   Hidroximetilglutaril-CoA-Reductasas NADP-Dependientes 
Descriptor Portuguese:   Hidroximetilglutaril-CoA-Redutases NADP-Dependentes 
Synonyms English:   3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent
HMG CoA-Reductases, NADP-Dependent
Hydroxymethylglutaryl-Coenzyme A Reductase (NADP)
3 Hydroxy 3 methylglutaryl coenzyme A reductase, NADP dependent
CoA-Reductases, NADP-Dependent HMG
HMG CoA Reductases, NADP Dependent
NADP-Dependent HMG CoA-Reductases
NADP-dependent Hydroxymethylglutaryl-CoA-Reductases
Hydroxymethylglutaryl-CoA-Reductase (NADP)  
Tree Number:   D08.811.682.047.820.150.415.750
Definition English:   Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis. 
Indexing Annotation English:   do not confuse with HYDROXYMETHYLGLUTARYL-COA REDUCTASES, NAD-DEPENDENT
Entry Combination - descr/qualif English:   Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent/antagonists & inhibitors use Hydroxymethylglutaryl-CoA Reductase Inhibitors
 
History Note English:   2002; use HYDROXYMETHYLGLUTARYL COA REDUCTASES (NM) 1981-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   36099 
Unique Identifier:   D025782 

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